The poxvirus F17 protein counteracts mitochondrially orchestrated antiviral responses
Abstract Poxviruses are unusual DNA viruses that replicate in the cytoplasm.To do so, they encode approximately 100 immunomodulatory proteins that counteract cytosolic nucleic acid sensors such as cGAMP synthase (cGAS) along with several other antiviral response pathways.Yet most of these immunomodulators are expressed very early in infection while